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某市污水厂抗生素和抗生素抗性基因的分布特征
摘要点击 3065  全文点击 874  投稿时间:2020-05-28  修订日期:2020-06-29
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中文关键词  污水厂  抗生素  抗生素抗性基因(ARGs)  分布特征  相关性
英文关键词  wastewater treatment plant  antibiotics  antibiotic resistance genes(ARGs)  distribution characteristics  correlation
作者单位E-mail
颉亚玮 浙江工业大学土木工程学院, 杭州 310023 xyw@zjut.edu.cn 
於驰晟 青岛大学环境科学与工程学院, 青岛 266071  
李菲菲 中国地质大学(北京)水资源与环境学院, 北京 100083  
姚鹏城 上海师范大学环境与地理科学学院, 上海 200234  
刘宏远 浙江工业大学土木工程学院, 杭州 310023 lhyzyy@zjut.edu.cn 
中文摘要
      抗生素和抗生素抗性基因(antibiotic resistance genes,ARGs)是国内外备受关注的新兴污染物.污水处理厂是环境中抗生素和ARGs的重要人为污染源.对某市6座主要污水处理厂进出水中抗生素和ARGs含量和特征的分析发现:6座污水厂进出水中检出7类73种抗生素.进水中抗生素总浓度为490.2~2288.6 ng·L-1,其中氧氟沙星、麻保沙星和罗红霉素这3种抗生素的检出频率最高.不同污水厂对抗生素去除效果差异较大,出水中抗生素总浓度为260.2~1464.3 ng·L-1,其中抗生素以喹诺酮类和大环内酯类为主,并且存在污水厂出水抗生素浓度高于进水抗生素浓度的现象.选择的10种目标ARGs在6座污水处理厂进出水中均有检出.sul Ⅰ基因的检出频率和丰度最高,绝对丰度为2.4×105~5.4×106 copies·mL-1;工业废水和生活污水中ARGs的总丰度无显著区别.与进水相比,出水中ARGs丰度和抗生素浓度的相关性显著变弱.
英文摘要
      Antibiotics and antibiotic resistance genes (ARGs) are highly concerning emerging polltants. Wastewater treatment plants (WWTPs) are considered to be one of the most important anthropogenic sources of antibiotics and ARGs in the environment. Six WWTPs of a city were selected to investigate the antibiotics and ARGs in the influents and effluents, respectively. In total, 73 kinds antibiotics belonging to 7 classes were detected in WWTPs. The total concentration of those antibiotics ranged between 490.2-2288.6 ng·L-1, and ofloxacin, maprofloxacin, and roxithromycin were the most frequently detected antibiotics in the influents. A dramtic difference was observed in the antibiotic removal efficiency among the WWTPs, and the total antibiotic concentration in the effluents ranged between 260.2-1464.3 ng·L-1. Macrolides and quinolones are the main classes in the effluents, and the antibiotic concentration in the effluents was higher than that in the influents. Ten kinds of ARGs were detected in the WWTPs. Among these, sul Ⅰ was the most widely prevalent with an absolute abundance of 2.4×105-5.4×106 copies·mL-1. No significant difference in ARG abundance was observed between industrial wastewater and domesic wastewater. Furthermore, the correlation between ARG abundance and antibiotic concentrations weakened after treatment in the WWTPs.

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