| 蔬菜中喹诺酮类抗生素污染探查与风险评价:以广州市超市蔬菜为例 |
| 摘要点击 1753 全文点击 2117 投稿时间：2010-08-25 修订日期：2010-10-25 |
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| 中文关键词 蔬菜 喹诺酮类抗生素 污染 HPLC-MS/MS 风险评价 |
| 英文关键词 vegetables quinolone antibiotics pollution HPLC-MS/MS risk assessment |
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| 中文摘要 |
| 基于超声提取-固相萃取(MW-SPE)预处理方法和高效液相色谱-串联质谱(HPLC-MS/MS)分析技术，对广州市超市蔬菜中4种喹诺酮类抗生素(QNs)的污染状况进行探查与健康风险评价.结果表明，4种喹诺酮类化合物的检出率均大于90%，蔬菜（干重，下同）中单个化合物最高含量约150 μg/kg，总含量(QNs)在10.16～193.25 μg/kg之间，平均为74.38 μg/kg，其中瓜果类(91.29 μg/kg)>根茎类(82.09 μg/kg)>叶菜类(52.30 μg/kg)，绿色蔬菜(104.49 μg/kg)>无公害蔬菜(79.06 μg/kg)>有机蔬菜(62.38 μg/kg)>普通蔬菜(61.23 μg/kg).食用蔬菜而摄入CIP＋ENR的平均值和最高值分别为1.8 μg和3.7μg，低于食用肉类而摄入CIP＋ENR的最高限值(10 μg).可见，蔬菜中普遍检出喹诺酮类抗生素，虽然其含量和健康风险相对较低，但其长期摄入与协同作用的潜在健康风险不容忽视. |
| 英文摘要 |
| Quinolones(QNs) including norfloxacin(NOR),enrofolxacin(ENR),ciprofloxacin(CIP) and lomefloxacin (LOM) in vegetables sampled from supermarkets of Guangzhou were determined using solid phase extraction and liquid chromatography-tandem mass spectrometry.The detected frequencies of four quinolone compounds in vegetables were all above 90%.The maximum concentration of individual compounds was about 150 μg/kg.Total concentrations of quinolones(QNs) ranged from 10.16 to 193.25 μg/kg(D.W.),with the average of 74.38 μg/kg and the orders for different kinds of vegetables as followed:melon-fruit vegetable (91.29 μg/kg)> rhizome vegetable (82.09 μg/kg)>leafy vegetable(52.30 μg/kg),and green vegetable(104.49 μg/kg)>pollution-free vegetable(79.06 μg/kg)>organic vegetable (62.38 μg/kg)>routinely cultivated vegetable(61.23 μg/kg).The average intake and the maximum intake of CIP＋ENR for human body via vegetable consumption were 1.8 μg and 3.7 μg respectively,which were lower than those with the maximum intake limit (10 μg) via meat consumption.So it can be concluded that quinolone antibiotics in vegetables were frequently detected.Though their concentrations and health risks to human body were relatively lower,potential health risk should not be neglected for long term intake and synergism of various antibiotics. |
