| 阴离子表面活性剂SDS和SDBS对紫贻贝生化指标的影响研究 |
| 摘要点击 2111 全文点击 1477 投稿时间：2006-01-27 修订日期：2006-02-21 |
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| 中文关键词 紫贻贝(Mytilus galloprovincialis) 十二烷基硫酸钠(SDS) 十二烷基苯磺酸钠(SDBS) 生物标志物 污染 |
| 英文关键词 Mytilus galloprovincialis sodium dodecylbenzene sulfonate sodium dodecyl sulfate biomarker contaminants |
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| 中文摘要 |
| 以青岛胶州湾现场调查数据为依据，选择阴离子表面活性剂十二烷基硫酸钠(SDS)和十二烷基苯磺酸钠(SDBS)作为污染物，以近海底栖生物紫贻贝为受试生物，研究了长期暴露后紫贻贝生化指标(SOD,CAT,GSH,GPx,GST,iNOS,AKP)的变化.结果表明，经过72 d不同浓度暴露后，SDBS实验组紫贻贝体内的SOD、CAT和iNOS活性均有显著下降（除CAT 0.1 mg/L组外），GSH、GST和GPx在3.0 mg/L SDS和SDBS组较各自对照组均有显著升高.SDBS对紫贻贝生化指标影响的显著性水平大于SDS. 统计分析显示，SDBS暴露组下GST与GPx呈显著正相关关系，iNOS与SOD也表现出一定正相关,但GSH与CAT、GSH与SOD呈现显著负相关关系.此外，结果发现后闭壳肌中iNOS可能是一个具有应用前景的阴离子表面活性剂暴露生物标志物. |
| 英文摘要 |
| We investigated anionic surfactants concentration in Jiaozhou Bay，China in May and August 2003.Two anionic surfactants sodium dodecylbenzene sulfonate (SDBS) and sodium dodecyl sulfate (SDS) were selected as contaminants to detect their effect on the biochemical indice in Mytilus galloprovincialis.Results show that after 72 days exposing,activities of superoxide dismutase (SOD),catalase (CAT) and induced nitric oxide synthase (iNOS) were significantly inhibited by challenged SDBS (except CAT activity in 0.1mg/L group). Activities of reduced glutathione (GSH),glutathione-S-transferase (GST) and glutathione peroxidase (GPx) were significantly higher than their corresponding control groups under 3.0 mg /L SDS and SDBS. Biochemical indice in Mytilus galloprovincialis were more easily effected by SDBS than by SDS. Statistical analysis suggested that significant positive relationships were found between GST and GPx,iNOS and SOD. But negative relationships were found between GSH and CAT,GSH and SOD under SBDS exposing. iNOS activity in the posterior adductor muscle may be a promising exposed biomarker in Mytilus galloprovincialis for anionic surfactants exposure. |
