| 四川省典型湖库沉积物中新污染物赋存特征与生态风险评估 |
| 摘要点击 1676 全文点击 72 投稿时间：2024-12-10 修订日期：2025-02-19 |
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| 中文关键词 四川省湖库 药物污染 新污染物 赋存特征 风险评估 |
| 英文关键词 lakes and reservoirs in Sichuan Province pharmaceutical contamination emerging contaminants occurrence characteristics risk assessment |
| DOI 10.13227/j.hjkx.202412100 |
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| 中文摘要 |
| 沉积物介质中频繁检出的药物类新污染物对生态环境及人类健康造成潜在威胁. 为了解四川省湖库沉积物中药物污染物的赋存情况及生态风险，采集22个典型中小湖库表层沉积物样本，通过超高效液相色谱-轨道阱质谱仪对22种常见药物化合物进行定量分析，采用风险商值法评估药物污染物的生态风险，并分析城市发展与污染物检出之间的相关性. 结果表明，磺胺类抗生素、抗炎药和降压药这3类药物的检出率为100%，22个湖库中药物新污染物总检出含量（以dw计）具有以下规律：磺胺类抗生素（111 μg·g-1）>抗炎药（37.8 μg·g-1）>喹诺酮类抗生素（18.9 μg·g-1）>β内酰胺类抗生素（6.30 μg·g-1）>霉素类抗生素（4.88 μg·g-1）>降压药（0.446 μg·g-1）>抗癫痫药（0.098 7 μg·g-1）. 磺胺类和喹诺酮类抗生素在各湖库占比分别为2.6%~80%和0.8%~36%. 磺胺胍和对乙酰氨基酚具有较高的生态风险，乙酰水杨酸、氧氟沙星和磺胺嘧啶这3种化合物呈中风险. 湖库沉积物中药物新污染物的分布及特征受区域人为活动影响显著，第一产业、畜牧业、水产业和人口数量对药物含量分布有较大影响. |
| 英文摘要 |
| Frequent detection of emerging pharmaceutical contaminants in sediment media poses potential threats to the ecological environment and human health. To understand the occurrence and ecological risks of pharmaceutical contaminants in sediments from lakes and reservoirs in Sichuan Province， surface sediment samples were collected from 22 typical small and medium-sized lakes and reservoirs. Quantitative analysis of 22 common pharmaceutical compounds was performed using ultra-high-performance liquid chromatography coupled with an Orbitrap Mass spectrometer， and the ecological risks of the pharmaceutical contaminants were assessed using the risk quotient method. The correlation between urban development and contaminant occurrence was also analyzed. The results showed that the detection rates of sulfonamide antibiotics， anti-inflammatory drugs， and antihypertensive drugs were 100%. The total detected concentrations of pharmaceutical emerging contaminants in the 22 lakes and reservoirs （expressed as dw） followed the order of sulfonamide antibiotics （111 μg·g-1） > anti-inflammatory drugs （37.8 μg·g-1） > quinolone antibiotics （18.9 μg·g-1） > β lactam antibiotics （6.30 μg·g-1） > macrolide antibiotics （4.88 μg·g-1） > antihypertensive drugs （0.446 μg·g-1） > antiepileptic drugs （0.098 7 μg·g-1）. The proportions of sulfonamide and quinolone antibiotics in individual lakes and reservoirs ranged from 2.6%-80% and 0.8%-36%， respectively. Sulfaguanidine and acetaminophen exhibited high ecological risks， and acetylsalicylic acid， ofloxacin， and sulfadiazine were categorized as medium-risk compounds. The distribution and characteristics of pharmaceutical emerging contaminants in lake and reservoir sediments were significantly influenced by regional anthropogenic activities， with primary industry， livestock farming， aquaculture， and population size having substantial impacts on their spatial distribution. |
