| 基于人体健康风险的水污染事件遗传性致癌物安全浓度研究 |
| 摘要点击 2418 全文点击 1769 修订日期：2011-06-23 |
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| 中文关键词 水污染事件 遗传性致癌物 短期暴露 人体健康风险 安全浓度 砷 |
| 英文关键词 water pollution accident genotoxic carcinogens short-term exposure human health risk assessment safety concentration arsenic |
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| 中文摘要 |
| 确定水污染事件中遗传性致癌物短期暴露安全浓度,是目前我国水环境管理中急需解决的问题. 在假设遗传性致癌物暴露剂量与致癌风险呈线性相关的前提下,提出了水体中遗传性致癌物安全浓度计算流程,建立了采用遗传性致癌物终生暴露安全浓度计算短期暴露安全浓度的方法.在我国2000~2010年间发生的60起水污染事故中,特征污染物为砷的水污染事件为6起,占总污染事件比例为10%,这一结果表明砷为我国水污染事件中高发的特征污染物.根据水污染事件遗传性致癌物短期暴露安全浓度计算方法,得出砷短期暴露安全浓度为0.5 mg·L-1,表明该方法在水污染事件应急管理中具有一定的可行性. |
| 英文摘要 |
| It was an urgent problem to determine short-term exposure safety concentration of genetic carcinogens in water pollution accident in China. Based on the hypothesis that the relationship between exposure dosage and carcinogenic risk was linear, the calculation process of genetic carcinogens safety concentration was put forwarded, and the method using life-time exposed safety concentration to calculate short-term exposure safety concentration was set up. Based on the statistical result of water pollution accident occurred in china during 2000-2010, arsenic was a major characteristic contaminate in water pollution accident. According to the method of short-term exposure safety concentration of genotoxic carcinogens, the safety concentration of arsenic was 0.5 mg·L-1, it showed that the method was feasible in emergence management of water pollution accident. |
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