| 长期施用粪肥蔬菜基地蔬菜中典型抗生素的污染特征 |
| 摘要点击 2847 全文点击 1348 投稿时间：2012-09-03 修订日期：2012-12-24 |
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| 中文关键词 蔬菜 抗生素 检出率 健康风险 食品安全 |
| 英文关键词 vegetables antibiotics detection rate health risk food safety |
| 作者 | 单位 | E-mail | | 吴小莲 | 暨南大学环境工程系, 广东省高校水土环境毒害性污染物防治与生物修复重点实验室, 广州 510632 | 221gte@163.com | | 向垒 | 暨南大学环境工程系, 广东省高校水土环境毒害性污染物防治与生物修复重点实验室, 广州 510632 | | | 莫测辉 | 暨南大学环境工程系, 广东省高校水土环境毒害性污染物防治与生物修复重点实验室, 广州 510632 | tchmo@jnu.edu.cn | | 姜元能 | 暨南大学环境工程系, 广东省高校水土环境毒害性污染物防治与生物修复重点实验室, 广州 510632 | | | 严青云 | 暨南大学环境工程系, 广东省高校水土环境毒害性污染物防治与生物修复重点实验室, 广州 510632 | | | 李彦文 | 暨南大学环境工程系, 广东省高校水土环境毒害性污染物防治与生物修复重点实验室, 广州 510632 | | | 黄献培 | 暨南大学环境工程系, 广东省高校水土环境毒害性污染物防治与生物修复重点实验室, 广州 510632 | | | 苏青云 | 东莞市农产品质量安全监督检测所, 东莞 523086 | | | 王纪阳 | 东莞市农产品质量安全监督检测所, 东莞 523086 | |
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| 中文摘要 |
| 利用高效液相色谱-串联质谱(HPLC-MS/MS)技术,分析了珠三角地区某长期施用粪肥蔬菜基地蔬菜中16种典型抗生素的含量,并初步评价其健康风险. 结果表明,绝大部分抗生素不同程度被检出,检出率为11%~100%,大多数含量<5 μg·kg-1(干重),最高为23.88 μg·kg-1,平均为0.91 μg·kg-1,以恩诺沙星、环丙沙星、磺胺二甲基嘧啶和磺胺嘧啶为主. 各蔬菜样品中至少检出1种抗生素,最多达10种. 蔬菜不同器官中喹诺酮类抗生素含量为地下部>地上部. 人体通过食用研究区蔬菜摄入抗生素的量低于日允许摄入量(ADI),表明其健康风险较小,但多种抗生素的联合毒性及其耐药性问题不容忽视. |
| 英文摘要 |
| Sixteen typical antibiotics including four tetracyclines,four quinolones,and eight sulfonamides in vegetables from manure-amended farm were determined using the ultra high performance liquid chromatography-tandem mass spectrometry and their health risks to human via the diet pathway was assessed. Most antibiotics were frequently detected in vegetable samples, with the detection rate from 11% to 90%. Concentrations of a single compound were mainly less than 5 μg·kg-1 (D. W.), with the maximum of 23.88 μg·kg-1 and the average of 0.91 μg·kg-1, respectively. Norfloxacin, ciprofloxacin, sulfamehtaoid and sulfadiazine were the dominant compounds. At least one antibiotic was detected in a single vegetable samples, and even up to ten antibiotics. The concentration of quinolones in underground parts was higher than those in aboveground parts. Intake dose of antibiotics via the consumption of the detected vegetables was lower than ADI, suggesting a lower health risk. But combination toxicity and resistance of antibiotics should not be ignored. |
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