| 广州市蔬菜中喹诺酮类抗生素污染特征及健康风险初步研究 |
| 摘要点击 3233 全文点击 1933 投稿时间：2009-12-03 修订日期：2010-03-22 |
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| 中文关键词 蔬菜 抗生素 喹诺酮类 污染 健康风险评价 |
| 英文关键词 vegetable antibiotics quinolones(QNs) pollution health risk assessment |
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| 中文摘要 |
| 采用高效液相色谱-荧光检测器（HPLC-FD）分析了广州市蔬菜中4种喹诺酮类抗生素的含量，并根据ADI值评估了蔬菜中喹诺酮抗生素污染对人体的健康风险. 结果表明，96%的市售蔬菜样品中不同程度地检出了喹诺酮抗生素，总含量为1.0～1683.1 μg/kg(鲜重)，高低顺序为叶菜类蔬菜＞瓜果类蔬菜＞根茎类蔬菜；4种喹诺酮类抗生素检出率大小顺序为NOR＞CIP＞LOM＞ENR；包括无公害蔬菜、绿色蔬菜和有机蔬菜在内的安全蔬菜样品中除恩诺沙星外，环丙沙星、洛美沙星、诺氟沙星和总含量均显著高于普通蔬菜；食用蔬菜对成人和儿童喹诺酮类抗生素ADI值（以CIP+ENR计）的最高贡献率分别高达41.5%和83%. |
| 英文摘要 |
| Quinolone antibiotics(QNs) including norfloxacin(NOR),enrofolxacin(ENR), ciprofloxacin(CIP) and lomefloxacin(LOM) in vegetable samples collected from Guangzhou were determined by high performance liquid chromatography (HPLC) coupled with fluorescent detector (FLD). The detected frequency of QNs was 96% in vegetables. The total concentration of quinolones(QNs) detected in vegetable ranged from 1.0 μg/kg to 1683.1 μg/kg(F.W.). Leafy vegetable topped the content of quinolones among the three types of vegetables, followed by the melon-fruit vegetable and rhizome vegetable. The detected frequency of the four quinolone antibiotics ranked as NOR＞CIP＞LOM＞ENR. Except ENR, concentrations of CIP,NOR,LOM and QNs in pollution-free vegetable, green vegetable and organic vegetable were higher than those in routine cultivated vegetables. The maximum contribution to ADI value（caculated by the sum of CIP and ENR）is estimated up to 41.5% and 83% for adults and children respectively via consumption of vegetables. |
