| 硝基芳烃对鲤鱼肝EROD活性影响的体外研究 |
| 摘要点击 1527 全文点击 1608 投稿时间：2000-12-15 |
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| 中文关键词 硝基芳烃 EROD 鲤鱼肝 环境毒理学 |
| 英文关键词 nitroaromtic hydrocarbon EROD liver of carp environmental toxicology |
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| 中文摘要 |
| 在体外实验条件下,研究了9种硝基芳烃化合物对鲤鱼肝脏7-乙氧基异吩唑酮-脱乙基酶(EROD)的影响.结果表明,9种硝基芳烃化合物对EROD均有激活作用,在实验浓度范围内,EROD活性与浓度之间存在剂量-效应关系.实验发现苯环上同一位置的取代基不同或同一取代基在苯环上的位置不同,对EROD的激活程度的影响也不同.
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| 英文摘要 |
| Nine nitroaromatic hydrocarbons (NAHs) induction of EROD activity was investigated by an in vitro assay based on carp (Cyprinus carpio) hepatic microsome system All nine NAHs tested were found to induce the activity of EROD There was dose effect relationship between EROD activity and concentrations of NAHs It was found that EROD activity was different, when different groups substituted at the same position of benzene ring, or the same group was at different position of benzene ring |
